Mechanisms of Human Disease

Subject PATH30001 (2010)

Note: This is an archived Handbook entry from 2010.

Credit Points: 12.50
Level: 3 (Undergraduate)
Dates & Locations:

This subject has the following teaching availabilities in 2010:

Semester 1, Parkville - Taught on campus.
Pre-teaching Period Start not applicable
Teaching Period not applicable
Assessment Period End not applicable
Last date to Self-Enrol not applicable
Census Date not applicable
Last date to Withdraw without fail not applicable

Timetable can be viewed here. For information about these dates, click here.
Time Commitment: Contact Hours: 36 lectures (3 per week)
Total Time Commitment: 120 hours (10 hours per week)

B. Science students:

Study Period Commencement:
Credit Points:
Study Period Commencement:
Credit Points:
Study Period Commencement:
Credit Points:
Semester 1, Semester 2
B. Biomedicine students:
Study Period Commencement:
Credit Points:
B. Biomedical Science students:
531-201 Basic Principles of Pathology (pre-2009)
Corequisites: Students wanting to complete a Major in Pathology must enrol in 531-302 Techniques for Investigation of Disease as a co-requisite with 531-301 Mechanisms of Human Disease.

Students completing other majors may enrol in 531-301 without 531-302.
Recommended Background Knowledge: For B.Science students: any of the following subjects would be helpful for your studies in Pathology -
Study Period Commencement:
Credit Points:
You could also consider other subjects offered by the Anatomy and Cell Biology or Pharmacology departments.
Non Allowed Subjects: None
Core Participation Requirements: For the purposes of considering request for Reasonable Adjustments under the Disability Standards for Education (Cwth 2005), and Students Experiencing Academic Disadvantage Policy, academic requirements for this subject are articulated in the Subject Description, Subject Objectives, Generic Skills and Assessment Requirements of this entry.
The University is dedicated to provide support to those with special requirements. Further details on the disability support scheme can be found at the Disability Liaison Unit website:


Dr Margaret Ayers


Dr Margaret Ayers:

Dr John Underwood:

Administrative Coordinator:

Mrs Katrina Rush

Subject Overview: This subject extends the concepts and examination of disease commenced in the second year subject ‘Exploring Human Disease’, with a focus on the following areas: cellular and molecular aspects of acute and chronic inflammatory diseases, a detailed analysis of the linkage between the acute inflammatory response and the innate and adaptive immune systems using immunodeficiency diseases as a model, immune-mediated disease, the effect of injury on the gastro-intestinal, renal and central nervous systems, genetic disorders, developmental and degenerative diseases and cancer.
Objectives: On completion of this subject students should have:
  • extended and deepened their understanding of the fundamental concepts involved in Pathology, begun in second year.
  • developed an understanding of the cellular and molecular bases of a variety of disease processes and their relationship to normal cellular and molecular structure and function.
  • considered both theoretical and practical ways in which research questions about these disease processes are formulated and investigated
  • Two multiple choice question tests during the semester (20%) each;
  • A 3 hour written examination in the examination period (60%).
Prescribed Texts: Kumar V. et al., Robbins and Cotran Pathologic Basis of Disease, latest edition, Saunders Elsevier.
Breadth Options:

This subject is not available as a breadth subject.

Fees Information: Subject EFTSL, Level, Discipline & Census Date
Generic Skills: At the end of this subject students should have developed the following skills:
  • the ability to understand and link complex overlapping and related ideas.
  • the ability to source, organise, read and understand reference material which covers a wide range of related and diverse topics about disease.
  • the ability to ask questions about complex processes which are currently under active investigation.
  • Science and Biomedicine students intending to take a major in Pathology are required to enrol in both 531-301 Mechanisms of Human Disease and 531-302 Techniques for Investigation of Disease. Science students must be familiar with the content of 531-201 Exploring Human Disease and have passes in the two 200-level Biochemistry prerequisites. Biomedicine students must be familiar with the Pathology and Biochemistry components of their 200-level core subject Molecular and Cellular Biomedicine.
  • Science students who do not want to do a Major in Pathology and do not have the Biochemistry prerequisites will be considered for entry into this subject on a case-by-case basis if they have appropriate marks in equivalent biomedical subjects.
  • This subject is available to both B.Science and B.Biomedicine students.
  • B.Biomedicine students doing a Defence & Disease major MUST consult the Major Information Booklet for additional corequisite choices.
Related Course(s): Bachelor of Science
Graduate Diploma in Biotechnology
Related Majors/Minors/Specialisations: Animal Cell Biology
Cell Biology
Defence and Disease
Human Structure and Function
Human Structure and Function

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