Microbes, Infections and Responses

This subject has the following teaching availabilities in 2015:

170 hours

BSc Students

BBiomedicine Students

Passes in the following two subjects:

None

The prerequisite subjects should have provided an appropriate background for this subject.

For the purposes of considering request for Reasonable Adjustments under the Disability Standards for Education (Cwth 2005), and Student Support and Engagement Policy, academic requirements for this subject are articulated in the Subject Overview, Learning Outcomes, Assessment and Generic Skills sections of this entry.

It is University policy to take all reasonable steps to minimise the impact of disability upon academic study, and reasonable adjustments will be made to enhance a student's participation in the University's programs. Students who feel their disability may impact on meeting the requirements of this subject are encouraged to discuss this matter with a Faculty Student Adviser and Student Equity and Disability Support: http://services.unimelb.edu.au/disability

This subject describes how microbes are an essential part of our environmental ecology and participate in unique interactions within their environmental niche. This subject also describes how microbes (bacteria, viruses, parasites) cause infections in humans, and how our immune system responds. The characteristics of some of the pathogens which cause respiratory, gastrointestinal, sexually transmissible and hospital acquired infections are discussed together with the body’s immune response to these pathogens, and the design of appropriate interventions, including vaccines and antimicrobials. The effects of both these infections and the interventions to control infectious diseases on communities and public health are also described so that the interaction between pathogen, host and environment can be illustrated.

This is a fully integrated subject in which the lectures and the practical classes build on, and support, each other. The practical classes comprise a series of case studies which illustrate and revise material covered in the lecture, and aim to teach the safe and effective implementation of basic microbiological techniques.

Upon completion of this subject, students should be able to:

• Describe the contributions and interactions of microbes within the environment
• Describe the characteristics of some medically important pathogens
• Describe the mechanisms by which microorganisms initiate infection and the mechanisms by which the immune response controls infection
• Describe some of the ways in which infectious disease can be controlled in individuals and in communities, including the use of antimicrobial agents and vaccines, and
• Perform basic microbiological techniques safely and effectively and recognise the clinical applications of these techniques

• Written practical reports throughout semester (15%),
• A 45-minute multiple choice question test mid semester (20%),
• Online quizzes (pre-practical class) throughout semester (5%)
• A 2-hour written exam in the end of the semester examination period (60%).

Attendance at practical classes is compulsory. Students who miss more than 20% of the practical component of this subject will not be eligible for final assessment.

Schaechter's Mechanisms of Microbial Disease (N C Engleberg, V DiRita and T S Dermody), 5th Edn, 2013

Prescott’s Microbiology, By Willey, Sherwood and Woolverton. Edn 9, 2014.

This subject is not available as a breadth subject.

On completion of this subject, students should have developed the following generic skills:

• An ability to interpret scientific literature.
• The capacity to integrate knowledge across disciplines.
• An ability to critically analyse scientific data.
• An ability to communicate scientific findings in written format.

Where appropriate:

• whilst students will not be involved in the manipulation and handling of animals, tissues obtained from appropriately euthanased animals will be used in some experiments.
• These experiments will be approved by the University of Melbourne Animal Welfare Committee.
• Experiments contained in this unit will also be approved by the Biosafety and Gene Technology Committee.

Students wishing to register in this subject after week 2 of a Semester should contact the subject coordinators.