Note: This is an archived Handbook entry from 2013.
|Dates & Locations:|| |
This subject is not offered in 2013.
|Time Commitment:||Contact Hours: None |
Total Time Commitment: 8-12 hours total study time per week
Study Period Commencement:
Not offered in 2013
|Recommended Background Knowledge:||None|
|Non Allowed Subjects:||None|
|Core Participation Requirements:||None|
Professor Phil Ryan, University of Adelaide
Biostatistics Collaboration of Australia
Academic Programs Office
Melbourne School of Population Health
Tel: +61 3 8344 9339
Fax: +61 3 8344 0824
Topics include: principles and methods of randomisation in controlled trials; treatment allocation, blocking, stratification and allocation concealment; parallel, factorial and crossover designs including n-of-1 studies; practical issues in sample size determination; intention-to-treat principle; phase I dose finding studies; phase II safety and efficacy studies; interim analysis and early stopping ; multiple outcomes/endpoints, multiple tests and subgroup analyses, including adjustment of significance levels and P-values; reporting trial results and use of the CONSORT statement.
|Objectives:||To enable students to understand and apply the principles of design and analysis of experiments, with a particular focus on randomised controlled trials (RCTs), to a level where they are able to contribute effectively as a statistician to the planning, conduct and reporting of a standard RCT.|
|Assessment:||Three written assignments submitted during the semester; Two worth 30% each (approx 10 hours work each) and one worth 40% (approx 12 hours work).|
|Prescribed Texts:||Piantadosi, S. Clinical Trials: A Methodological Perspective, 2nd ed, John Wiley & Sons, New York, 2005 (ISBN 978-0-471-72781-1) |
Resources Provided to Students: Printed course notes and assignment material by mail, email, and online interaction facilities.
|Breadth Options:|| |
This subject is not available as a breadth subject.
|Fees Information:||Subject EFTSL, Level, Discipline & Census Date|
Independent problem solving, critical appraisal of research literature, clarity of written expression, sound communication of technical concepts
|Links to further information:||http://www.sph.unimelb.edu.au|
This subject is not available in the Master of Public Health.
Master of Biostatistics |
Postgraduate Certificate in Biostatistics
Postgraduate Diploma in Biostatistics
Download PDF version.