Mechanisms of Human Disease

Subject PATH30001 (2011)

Note: This is an archived Handbook entry from 2011.

Credit Points: 12.50
Level: 3 (Undergraduate)
Dates & Locations:

This subject has the following teaching availabilities in 2011:

Semester 1, Parkville - Taught on campus.
Pre-teaching Period Start not applicable
Teaching Period not applicable
Assessment Period End not applicable
Last date to Self-Enrol not applicable
Census Date not applicable
Last date to Withdraw without fail not applicable

Timetable can be viewed here. For information about these dates, click here.
Time Commitment: Contact Hours: 36 lectures (3 per week)
Total Time Commitment: 120 hours (10 hours per week)

B. Science students:

Study Period Commencement:
Credit Points:
Study Period Commencement:
Credit Points:
Semester 1, Semester 2
Study Period Commencement:
Credit Points:
Semester 1, Semester 2
B. Biomedicine students:
Study Period Commencement:
Credit Points:
B. Biomedical Science students:
531-201 Basic Principles of Pathology (pre-2009)
Corequisites: Students wanting to complete a Major in Pathology must enrol in PATH30002 Techniques for Investigation of Disease as a co-requisite with PATH30001 Mechanisms of Human Disease.

Students completing other majors may enrol in PATH30001 without PATH30002.
Recommended Background Knowledge: None
Non Allowed Subjects: None
Core Participation Requirements: For the purposes of considering request for Reasonable Adjustments under the Disability Standards for Education (Cwth 2005), and Students Experiencing Academic Disadvantage Policy, academic requirements for this subject are articulated in the Subject Description, Subject Objectives, Generic Skills and Assessment Requirements of this entry.
The University is dedicated to provide support to those with special requirements. Further details on the disability support scheme can be found at the Disability Liaison Unit website:


Dr Margaret Ayers


Dr Margaret Ayers:

Administrative Coordinator:

Subject Overview: This subject extends the concepts and examination of disease commenced in the second year subject ‘Exploring Human Disease’, with a focus on the following areas: cellular and molecular aspects of acute and chronic inflammatory diseases, a detailed analysis of the linkage between the acute inflammatory response and the innate and adaptive immune systems using immunodeficiency diseases as a model, immune-mediated disease, the effect of injury on the gastro-intestinal, renal and central nervous systems, genetic disorders, developmental and degenerative diseases and cancer.
Objectives: On completion of this subject students should have:
  • extended and deepened their understanding of the fundamental concepts involved in Pathology, begun in second year.
  • developed an understanding of the cellular and molecular bases of a variety of disease processes and their relationship to normal cellular and molecular structure and function.
  • considered both theoretical and practical ways in which research questions about these disease processes are formulated and investigated
  • Two multiple choice question tests during the semester (20%) each;
  • A 3 hour written examination in the examination period (60%).
Prescribed Texts: Kumar V. et al., Robbins and Cotran Pathologic Basis of Disease, latest edition, Saunders Elsevier.
Breadth Options:

This subject is not available as a breadth subject.

Fees Information: Subject EFTSL, Level, Discipline & Census Date
Generic Skills: At the end of this subject students should have developed the following skills:
  • the ability to understand and link complex overlapping and related ideas.
  • the ability to source, organise, read and understand reference material which covers a wide range of related and diverse topics about disease.
  • the ability to ask questions about complex processes which are currently under active investigation.
  • Science and Biomedicine students intending to take a major in Pathology are required to enrol in both PATH30001 Mechanisms of Human Disease and PATH30002 Techniques for Investigation of Disease. Science students must be familiar with the content of PATH20001 Exploring Human Disease and have passes in the two 200-level Biochemistry prerequisites. Biomedicine students must be familiar with the Pathology and Biochemistry components of their 200-level core subject Molecular and Cellular Biomedicine.
  • Science students who do not want to do a Major in Pathology and do not have the Biochemistry prerequisites will be considered for entry into this subject on a case-by-case basis if they have appropriate marks in equivalent biomedical subjects.
  • This subject is available to both B.Science and B.Biomedicine students.
  • B.Biomedicine students doing a Defence & Disease major MUST consult the Major Information Booklet for additional corequisite choices.
Related Course(s): Bachelor of Science
Related Majors/Minors/Specialisations: Animal Cell Biology (specialisation of Cell and Developmental Biology major)
Cell Biology (pre-2008 Bachelor of Science)
Defence and Disease
Human Structure and Function
Science credit subjects* for pre-2008 BSc, BASc and combined degree science courses

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