Note: This is an archived Handbook entry from 2011.
|Dates & Locations:|| |
This subject has the following teaching availabilities in 2011:Semester 2, Parkville - Taught on campus.
Timetable can be viewed here. For information about these dates, click here.
|Time Commitment:||Contact Hours: three x 1 hour lecture and one x 1 hour tutorial per week |
Total Time Commitment:
48 contact hours with an estimated total time commitment of 120 hours (including non-contact time).
BSc students |
Biochemistry & Molecular Biology Part A (521-211)
Biochemistry & Molecular Biology Part B (521-212)
2009 and subsequently:
Study Period Commencement:
Semester 1, Semester 2
Study Period Commencement:
|Recommended Background Knowledge:||None|
|Non Allowed Subjects:||Students cannot enrol in and gain credit for this subject if previously obtained credit for pre-2009 subject (521-301) Protein Structure, Design and Engineering.|
|Core Participation Requirements:||For the purposes of considering request for Reasonable Adjustments under the Disability Standards for Education (Cwth 2005), and Students Experiencing Academic Disadvantage Policy, academic requirements for this subject are articulated in the Subject Description, Subject Objectives, Generic Skills and Assessment Requirements of this entry. |
The University is dedicated to provide support to those with special requirements. Further details on the disability support scheme can be found at the Disability Liaison Unit website:
CoordinatorAssoc Prof Paul Gooley
This subject will describe the wide range of structures, functions and interactions of proteins and their importance in biological processes, biomedicine and biotechnology. Emphasis will be on the three-dimensional structure of proteins and their interactions with peptides, proteins, lipids, nucleic acids and other physiologically important molecules. We will describe experimental and computational techniques and how they help in determining and predicting protein structure and function, aid the design of new proteins and are used to develop new drugs. The subject matter addresses the general properties of protein structure; the major classes and topologies of proteins; evolution of sequence, structure and function; protein synthesis, folding, misfolding, targeting and trafficking; protein engineering for biotechnology; bioinformatics analysis of protein sequence and structure; binding of small molecules to proteins and drug design; protein-protein interactions; effects of mutations on tertiary structure, protein stability and biological functions; enzyme reaction kinetics and mechanisms. This subject is required for completion of a major in Biochemistry and Molecular Biology.
By the end of the subject the student should develop a critical appreciation of the current literature on protein structure and function. The student should understand and appreciate:
Proteins Structure and Function, David Whitford, 2007 (John Wiley and Sons Ltd ISBN-13: 978-0671-49893-0)
|Breadth Options:|| |
This subject is not available as a breadth subject.
|Fees Information:||Subject EFTSL, Level, Discipline & Census Date|
On completion of this subject, students should have developed the following generic skills:
Students enrolled in the BSc (pre-2008 BSc), BASc or a combined BSc course will receive science credit for the completion of this subject.
Students undertaking this subject will be expected to regularly access an internet-enabled computer.
Bachelor of Science |
Biochemistry and Molecular Biology |
Biomedical Biotechnology (specialisation of Biotechnology major)
Biotechnology (pre-2008 Bachelor of Science)
Science credit subjects* for pre-2008 BSc, BASc and combined degree science courses
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