Note: This is an archived Handbook entry from 2008.Search for this in the current handbook
|Dates & Locations:|| |
This subject has the following teaching availabilities in 2008:Semester 2, - Taught on campus.
Timetable can be viewed here. For information about these dates, click here.
|Time Commitment:||Contact Hours: 12 lectures (two per week for six weeks) and 36 hours of practical workshops (one 6-hour session per week for six weeks) during the second half of Semester 2 |
Total Time Commitment: 120 hours
|Prerequisites:||534-301 Cellular and Molecular Pharmacology; exemption may be given at the discretion of the Head of Department. Some 200-level chemistry is desirable, preferably 610-210 or 610-221.|
|Recommended Background Knowledge:||None|
|Non Allowed Subjects:||None|
|Core Participation Requirements:||It is University policy to take all reasonable steps to minimise the impact of disability upon academic study and reasonable steps will be made to enhance a student’s participation in the University’s programs. This subject requires all students to actively and safely participate in laboratory activities. Students who feel their disability may impact upon their participation are encouraged to discuss this with the subject coordinator and the Disability Liaison Unit.|
CoordinatorDr R A Hughes
|Subject Overview:|| |
The teaching program will introduce students to the means by which new drugs can be discovered. The lectures will cover the following topics: historical background; choice of therapeutic target; screening; rational drug design; molecular modelling; quantitative structure-activity relationships; the emerging role of combinatorial chemistry; peptide-based drug design; recombinant proteins as drugs; novel delivery systems; in-vitro and in-vivo assays; high throughput assays; and the impact of molecular biology on drug discovery. In the practicals, students will develop skills in the use of computer-aided molecular modelling to understand drug and receptor structure and how this knowledge can be applied to the design of new drugs, and examine case studies of modern drug discovery. Students will be encouraged to integrate knowledge from different parts of the subject, reinforcing the need for a multidisciplinary approach to the discovery and development of new drugs.
|Assessment:||Ongoing assessment of practical work during the semester (25%); a 2-hour written examination in the examination period (75%).|
|Breadth Options:|| |
This subject is not available as a breadth subject.
|Fees Information:||Subject EFTSL, Level, Discipline & Census Date|
|Generic Skills:|| |
Upon completion of this subject students should develop skills in:
|Notes:||Students enrolled in the BSc (pre-2008 BSc), BASc or a combined BSc course will receive science credit for the completion of this subject.|
Bachelor of Arts and Bachelor of Science |
Bachelor of Arts and Sciences
Bachelor of Biomedical Science
Bachelor of Science
Graduate Diploma in Biotechnology
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