Note: This is an archived Handbook entry from 2012.
|Dates & Locations:|| |
This subject has the following teaching availabilities in 2012:Semester 1, Parkville - Taught on campus.
Timetable can be viewed here. For information about these dates, click here.
|Time Commitment:||Contact Hours: 3 x one hour lectures per week (total contact hours: 36) |
Total Time Commitment:
Study Period Commencement:
Study Period Commencement:
Students wishing to undertake this subject as breadth will need the approval of the subject co-ordinator.
|Recommended Background Knowledge:|| |
|Non Allowed Subjects:|| |
This subject cannot be taken if credit has been previously obtained for:
|Core Participation Requirements:||
For the purposes of considering request for Reasonable Adjustments under the Disability Standards for Education (Cwth 2005), and Students Experiencing Academic Disadvantage Policy, academic requirements for this subject are articulated in the Subject Description, Subject Objectives, Generic Skills and Assessment Requirements of this entry.
CoordinatorAssoc Prof Richard Hughes, Dr Michael Lew
Assoc Prof Richard Hughes
Dr Michael Lew
Ms Hong Nguyen
Modern rational drug discovery and development is a coordinated, multidisciplinary undertaking. This subject will introduce students to the basic science, including aspects of cellular and molecular pharmacology such as drug-receptor interactions, cell signalling, absorption-distribution-metabolism-excretion (ADME) and toxicology/safety pharmacology.
A variety of techniques used at each stage of the drug development process will be presented, such as quantitative structure -activity relationships (QSAR), combinatorial chemistry, high throughput screening, integrated pharmacological assays and clinical trial design. Consideration will also be given to executive strategies underpinning this enterprise, such as scientific and economic aspects of target choice, lead optimisation and pharmacogenomics.
Students will be encouraged to integrate knowledge from different parts of the subject and their course, reinforcing the multidisciplinary nature of drug discovery and development.
Upon completion of this subject, students will have:
They will gain an appreciation of how modern drug discovery and development brings together input from a range of disciplines, including chemistry, structural biology, pharmacology and clinical sciences.
|Prescribed Texts:|| |
Pharmacology, Rang et al., Churchill Livingstone, 6th edition, 2007.
|Breadth Options:|| |
This subject potentially can be taken as a breadth subject component for the following courses:
You should visit learn more about breadth subjects and read the breadth requirements for your degree, and should discuss your choice with your student adviser, before deciding on your subjects.
|Fees Information:||Subject EFTSL, Level, Discipline & Census Date|
By the end of this subject, students will:
This subject is available to students enrolled in the pre 2008 BSc, New Generation BSc, Biomedicine degree.
Biomedical Biotechnology (specialisation of Biotechnology major) |
Biotechnology (pre-2008 Bachelor of Science)
Medicinal Chemistry (specialisation of Chemistry major)
Science credit subjects* for pre-2008 BSc, BASc and combined degree science courses
Science-credited subjects - new generation B-SCI and B-ENG. Core selective subjects for B-BMED.
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