Clinical Neuroscience Res. & Imaging

This subject has the following teaching availabilities in 2016:

170 hours per 12.5 credit point subject.

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To enrol in this subject, you must be admitted in N01AA, N34AA, or N05NS. This subject is not available for students admitted in any other courses.

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For the purposes of considering requests for Reasonable Adjustments under the Disability Standards for Education (Commonwealth 2005), and Students Experiencing Academic Disadvantage Policy, academic requirements for this course are articulated in the Course Overview, Objectives and Generic Skills sections of this entry.

It is University policy to take all reasonable steps to minimise the impact of disability upon academic study, and reasonable adjustments will be made to enhance a student's participation in the University's programs. Students who feel their disability may impact on meeting the requirements of this course are encouraged to discuss this matter with the Student Equity and Disability Support Team: http://www.services.unimelb.edu.au/disability/

Topics covered in this subject include:
• Frontiers in clinical neuroscience research;
• Expert briefings on the current research questions in epilepsy, intellectual disability and autism, stroke and multiple sclerosis;
• Research methods in clinical neurological genetics;
• How animal models can inform clinical neuroscience research;
• Research methods in clinical neuropharmacology;
• Brain development;
• Neuroplasticity and neurotrophic factors research;
• Research methods in neurodegenerative disorders;
• Clinical trials methods;
• How clinical research informs basic research and vice-versa;
• Research methods in neurological epidemiology;
• Research methods in neurological rehabilitation;
• Translation of clinical research findings into practice.
• Expert briefings on the current research questions in dementias, movement disorders, schizophrenia and bipolar disorders;
• Major emphasis on cutting-edge human imaging techniques;
• Cognitive functioning;
• Research techniques in clinical neurophysiology;
• Introduction to neuroimaging techniques;
• Principles of magnetic resonance imaging (MRI);
• Practical demonstration of language functional MRI;
• Structural MR imaging and clinical research applications;
• Functional MR imaging and clinical research applications;
• Analysis of MR imaging;
• Magnetic resonance spectroscopy and research applications; and
• New frontiers in multi-disciplinary clinical neuroscience research.

Students who successfully complete this specialist subject will:
• Demonstrate a high level of understanding of a wide variety of clinical research methodologies applicable to problems in neurological disease,
• Have a sound knowledge of the overlap with basic science advances across the neuroscience field and a good understanding of clinical synergies,
• Have gained insights into the broad “hot topics” in neuroscience research and be able to generate useful discussions and ideas,
• Be able to analyse and critically appraise the clinical and basic neuroscience literature in a chosen topic of interest,
• Be able to apply this knowledge through creating new ideas for clinical research projects, and
• Be able to work in teams and effectively communicate clinical research findings.
• Demonstrate a high level of understanding of various advanced clinical research techniques that have broad application to many areas of neuroscience;
• Understand clinical research applications of brain imaging techniques;
• Understand the need for multi-disciplinary integration in clinical research and be able to establish appropriate collaborations across disciplines;
• Have gained insights into current research applications of these techniques across the various neuroscience disciplines;
• Be able to develop innovative strategies to investigate clinical neuroscience research questions to pursue in response to particular neurological problems; and
• Have achieved a level of competency enabling them to create and conduct high quality clinical neuroscience research projects from the original concept through to submission of competitive research proposals.

• Neuroscience research skills
  Oral team presentation (total 20 mins + 10 mins discussion) based on published clinical neuroscience research topics discussed within multi-disciplinary teams (10 percent), a comprehensive literature review in a chosen clinical neuroscience research area leading to explicit conclusions and new research questions to pursue (max. 3500 words) (40 percent).
  This assessment will be undertaken at the end of the first week of the teaching period.
• Neuroimaging skills
  A short oral presentation of a proposed research plan (15 percent), a comprehensive clinical neuroscience project proposal formatted as a grant submission, including potential multi-disciplinary collaborations and drawing on the course contents (and previous professional experience if relevant) (3000 words) (35 percent).
  This assessment will be undertaken at the end of the second week of the teaching period (the second week is taught three months after the first week).

As part of their course materials students will be provided with articles and references that support the teaching.

This subject is not available as a breadth subject.

Students will gain the following skills that can be used more broadly in their workplace:
• Clinical research skills
• Critical evaluation skills
• Presentation skills
• How to undertake a literature review
• How to prepare a grant application
• Greater understanding of translation of research findings into clinical outcomes