Genetic Epidemiology
Subject 505-926 (2008)
Note: This is an archived Handbook entry from 2008.Search for this in the current handbook
| Credit Points: | 12.500 | ||||||||||||
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| Level: | Graduate/Postgraduate | ||||||||||||
| Dates & Locations: | This subject has the following teaching availabilities in 2008: Semester 2, - Taught on campus.
Classroom or Distance Timetable can be viewed here. For information about these dates, click here. | ||||||||||||
| Time Commitment: | Contact Hours: Classroom: 2 hours per week. Distance: 2 hours per week via internet. Total Time Commitment: Students will be expected to undertake additional study (i.e. outside the stated contact hours) of at least 4-5 hours per week. | ||||||||||||
| Prerequisites: | 505-969 Epidemiology and Analytic Methods I, or equivalent 505-970 Epidemiology and Analytic Methods II, or equivalent 505-973 Study Design in Epidemiology | ||||||||||||
| Corequisites: | None | ||||||||||||
| Recommended Background Knowledge: | None | ||||||||||||
| Non Allowed Subjects: | None | ||||||||||||
| Core Participation Requirements: | Special Computer Skills Required: Proficiency with a Web browser and basic word processing skills Resources provided to Distance students: A tutor will be assigned to each student. Lecture notes will be provided on a Website that can be printed by the student. A set of reading material will be mailed to each student prior to the start of semester. An electronic forum service will be provided. |
Coordinator
Centre for MEGA Epidemiology, Pop Hlth| Subject Overview: | The majority of chronic diseases share a common risk factor: the family history for that disease. Epidemiologists can use families to assess the role of the interrelated genetic and environmental risk factors. This subject provides an introduction to epidemiological methods which are used to help identify genes associated with disease, and to estimate what proportion of the disease can be attributed to measured or unmeasured genetic factors. Concepts, methodologies, and interpretation of familial risk factors for chronic diseases are the major topics in this subject. Topics covered include introduction to population genetics, introduction to molecular genetics, design of family studies including both twin and pedigree studies, segregation analysis, linkage, association studies, estimating the magnitude of the gene effect on disease susceptibility, and genetic screening. On completion of this subject, students should be able to: understand that susceptibility to complex diseases is due to both genetic and environmental factors; understand the relationship between familial aggregation of disease and genetic aetiology; understand that genes can be altered in various ways with varying effects on molecular function; understand the fundamentals and limitations of studies designed to identify genes that influence disease susceptibility; determine the significance of disease susceptibility genes in the risk of disease; critically appraise a genetic epidemiology study; appreciate that genetic epidemiology is a developing field with a high degree of statistical modelling; and understand a variety of techniques to find genes for disease using epidemiological studies. |
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| Assessment: | Tutorial participation (10%), one written assignment of 2,000 words (40%) due mid-semester and one written assignment of 2,500 words (50%) due end semester. |
| Prescribed Texts: | None Special Computer Requirements :For students studying via Distance Mode Access to computer with Netscape or Microsoft Internet Explorer and print access. An e-mail account is also required. Lecture notes will be provided via internet and tutorials will be conducted over the internet |
| Recommended Texts: | None |
| Breadth Options: | This subject is not available as a breadth subject. |
| Fees Information: | Subject EFTSL, Level, Discipline & Census Date |
| Generic Skills: | Subject Level: 500 |
| Links to further information: | http://www.sph.unimelb.edu.au |
| Notes: | This subject is a Group 1 elective in the Master of Public Health. Subject Coordinator: Dr Mark Jenkins 8344 0902 |
| Related Course(s): |
Master of Epidemiology Master of Public Health |
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